Robert M. Kaplan is a faculty member at Stanford Medicine's Clinical Excellence Research Center and a distinguished professor emeritus at the UCLA Fielding School of Public Health. A serious adverse reaction rate of 1/100,000 was more likely to discourage vaccine use in comparison to rates of 1/million or 1/100 million. Robert M. Kaplan, Ph.D. is Fred W. and Pamela K. Wasserman Distinguished Professor of the Department of Health Services at UCLA and Distinguished Professor of Medicine at the UCLA David Geffen School of Medicine. Baseline data (collected in April-December 2004, analyzed in 2006) included demographics, medical history, the Quality of Well-Being Scale (QWB-SA), a timed 400-m walk, and the Short Physical Performance Battery (SPPB). Wanigatunga, A. Systems Delivery Innovation for Alzheimer Disease. View details for DOI 10.1016/j.amepre.2018.09.006, View details for Web of Science ID 000453383700020, View details for Web of Science ID 000498593400292. Participants in the physical activity group who were 80 years or older (n=307) and those with poorer baseline physical performance (n=328) had better changes in executive function composite scores compared with the health education group (P=.01 for interaction for both comparisons). View details for DOI 10.1371/journal.pone.0116058. The probability of minor side effects (50%, 75%, 90%) including fever and sore arm, did not significantly influence likelihood of receiving the vaccine. Prevalence rates were 33.0% for insomnia, 18.1% for daytime drowsiness, 47.8% for poor sleep quality, and 32.9% for high risk of sleep apnea. In addition, consistent indexing in databases, such as MEDLINE, would allow for better matching of records and publications, leading to increased utility of these searches for systematic review projects. We randomized a volunteer sample of 1635 sedentary men and women aged 70 to 89 years who had physical limitations, defined as a score on the Short Physical Performance Battery of 9 or below, but were able to walk 400 m.Participants were randomized to a structured, moderate-intensity physical activity program (n=818) conducted in a center (twice/wk) and at home (3-4 times/wk) that included aerobic, resistance, and flexibility training activities or to a health education program (n=817) consisting of workshops on topics relevant to older adults and upper extremity stretching exercises.The primary outcome was major mobility disability objectively defined by loss of ability to walk 400 m.Incident major mobility disability occurred in 30.1% (246 participants) of the physical activity group and 35.5% (290 participants) of the health education group (hazard ratio [HR], 0.82 [95% CI, 0.69-0.98], P=.03).Persistent mobility disability was experienced by 120 participants (14.7%) in the physical activity group and 162 participants (19.8%) in the health education group (HR, 0.72 [95% CI, 0.57-0.91]; P=.006). Using a 3 * 3 * 3 factorial experimental design, we estimated the impact of three factors: probability of 1) protection against COVID-19, 2) minor side effects, and 3) a serious adverse reactions. We considered subject inclusion and exclusion criteria; numbers of subjects enrolled and the proportion in the primary analyses; inclusion of a Consolidated Standards of Reporting Trials (CONSORT) flow diagram; use of random assignment; use of placebo control conditions; lengths of treatment and follow-up; primary outcome variable; trial registration; journal impact factor.STUDY SELECTION: Studies indexed as efficacy AND 'real-world' AND depression or effectiveness AND 'real-world' AND depression in PubMed up to 18 May 2019.FINDINGS: 27 studies met the inclusion criteria: 13 effectiveness studies, 6 efficacy studies and 8 studies indexed as both effectiveness and efficacy. Most studies had data that could have been analysed and reported. Dismiss. Mr. Kaplan holds degrees from Cape Town University and Columbia University. PURPOSE: Health care expenditures and biomedical research funding are often justified by the belief that modern health care powerfully improves life expectancy in wealthy countries. TRICARE follows the predominant payment model in the USA-fee-for-service-although the Department of Defense (DoD) and Congress encourage and mandate a move toward alternative payment models-mainly, fee-for-value. Journalist and geopolitical analyst Robert Kaplan on the South China Sea, China and Asia's future. Designers and architects created the rule 'form follows function (FFF)' for their own profession. Council on Foreign Relations Council on Foreign Relations (CFR), independent nonpartisan think tank and publisher that promotes . Healthy older adults were randomly selected from a large community health project and the groups were compared on measures of quality of life, autonomic activity (heart rate, heart rate variability, skin conductance response, respiratory amplitude/rate), immune function (secretory Immunoglobulin A, sIgA), stress hormone (cortisol) and brain imaging (resting state functional connectivity, structural differences). Kaplan and Saccuzzo's engaging and thorough text demonstrates how psychological tests are constructed and used, both in a professional setting and in everyday lives. Responses ranged from 0 (none of the time) to 5 (all of the time). Two different functions (confirmation and exclusion) of both perceptions (Perceived Anxiety and Safety) can be quantified with those calculations.The analysis of six published tests and of one incompletely reported test on COVID-19 polymerase chain reactions (completed by four assumptions on high and low sensitivities and specificities) demonstrated that none of these tests induces 'Perceived Safety'. Robert A Kaplan, age 70. Dr Robert M Kaplan is a company that operates in the Hospital & Health Care industry. O zpase. 416 (57.4%) of the studies posted some results. Health care remains the most expensive sector in the U.S. economy, now accounting for nearly 1 in every 5 dollars spent. B., Pellegrini, C. A., Chen, S., Allore, H. G., Miller, M. E. Cost-effectiveness of the LIFE Physical Activity Intervention for Older Adults at Increased Risk for Mobility Disability. These mixed results might reflect heterogeneity in response to physical activity, with some subgroups of individuals responding positively, but not others.1) To examine the impact of genetic variation and sex on changes in depressive symptoms in older adults after a physical activity (PA) intervention, and 2) to determine if PA differentially improves particular symptom dimensions of depression.Randomized controlled trial.Four field centers (Cooper Institute, Stanford University, University of Pittsburgh, and Wake Forest University).396 community-dwelling adults aged 70-89 years who participated in the Lifestyle Interventions and Independence for Elders Pilot Study (LIFE-P).12-month PA intervention compared to an education control.Polymorphisms in the serotonin transporter (5-HTT), brain-derived neurotrophic factor (BDNF), and apolipoprotein E (APOE) genes; 12-month change in the Center for Epidemiologic Studies Depression Scale total score, as well as scores on the depressed affect, somatic symptoms, and lack of positive affect subscales.Men randomized to the PA arm showed the greatest decreases in somatic symptoms, with a preferential benefit in male carriers of the BDNF Met allele. South African Medical Journal March 2001, 90-3;216-217.] The total time a patient is disabled likely has a greater influence on his or her quality of life than the initial occurrence of disability alone.To compare the effect of a long-term, structured physical activity program with that of a health education intervention on the proportion of patient assessments indicating major mobility disability (MMD) (that is, MMD burden) and on the risk for transitions into and out of MMD.Single-blinded, parallel-group, randomized trial. View details for Web of Science ID 000431185201257. American science produces the bestand most expensivemedical treatments in the world. This narrative review explores conceptual issues, and inconsistencies between evidence and opinion about screening.We examined the interpretation of screening studies in relation to three intellectual traditions: (1) The relationship between prevention and cure; (2) Confirmation bias and the challenge of incorporating new data: less care may produce better outcomes than more care; (3) The answers to three structured questions about efficacy, effectiveness, and value of treatments proposed by Sir Archie Cochrane and Sir Austin Bradford Hill.When considering extensions of life expectancy or all-cause mortality, systematic reviews typically show cancer screening to have only small effects and often non-significant effects on all-cause mortality. Botoseneanu, A., Ambrosius, W. T., Beavers, D. P., De Rekeneire, N., Anton, S., Church, T., Folta, S. C., Goodpaster, B. H., King, A. C., Nicklas, B. J., Spring, B., Wang, X., Gill, T. M. Combined Reduced Forced Expiratory Volume in 1 Second (FEV1) and Peripheral Artery Disease in Sedentary Elders With Functional Limitations. The odds of having MetS or its individual components were similar in obese and nonobese, combined or not with dynapenia (nonsignificant odds ratio [95% confidence interval]).Nonobese dynapenic older adults had fewer metabolic disease risk factors than nonobese and nondynapenic older adults. Fremont, A., Kim, A. Y., Bailey, K., Hanley, H. R., Thorne, C., Dudl, R. J., Kaplan, R. M., Shortell, S. M., DeMaria, A. N. Educational Attainment and Health Outcomes: Data From the Medical Expenditures Panel Survey, Dynapenia and Metabolic Health in Obese and Nonobese Adults Aged 70 Years and Older: The LIFE Study. The absence of interaction effects suggests that respondents consider the side effects and benefits independently. Time spent watching television was positively associated with BMI, while reading and computer use were not. In the Lifestyle Interventions and Independence for Elders cohort, their external validity was further demonstrated by associations with other risk factors for cognitive dysfunction: education, hypertension, diabetes, and physical function. This pilot work examined associations of brain grey matter volumes (GMV) with perceived fatigability in older adults to elucidate disablement mechanisms. The incremental cost-effectiveness ratios were US$42,376/major mobility disability prevented and US$49,167/QALY. Despite enthusiasm for cancer screening, systematic reviews consistently fail to show that screening reduces all-cause mortality. To control for confounding of group participation with survival (because individual sessions preceded group), we used risk set sampling to match minimal survival time of those receiving or not receiving group training.Analyses correcting for differential survival among comparison groups showed that group plus individual therapy was associated with a 33% reduction (hazard ratio=0.67; 95% confidence interval, 0.49-0.92, P=.01) in medical outcome compared to usual care. Last updated 4 months ago. A preliminary cost/effectiveness analysis gauged the cost/disability avoided to be $28,206. Robert D. Kaplan Dr. Duyeon Kim Dr. Daniel Kliman Michael Kofman Christopher D. Kolenda Margarita "Rita" Konaev Steven Kosiak Dr. Andrew F. Krepinevich, Jr. Peter L. Levin Jennifer McArdle Brendan McCord Dr. ED McGrady Jack Midgley J Travis Mosier Dr. Go Myong-Hyun Catherine A. Novelli Dr. John Park Ben Renda Elina Ribakova Diem Salmon However, evidence is inconclusive regarding the influence of this polymorphism on older adults' functional responses to exercise. Jobs People Learning Dismiss Dismiss. Follow-up ended in December 2013. Results of prior research have been mixed, including findings of a 3:1 incidence ratio for males vs. females, but increasing AS rates among females.METHODS: We estimated the incidence of AS in a retrospective cohort study of diverse, working-age US military service members during March 2014 - June 2017 (N = 728,556) who underwent clinical practice guideline-directed screening for chronic back pain. We compared two groups of older adults with 10 years of mindfulness meditation (integrative body-mind training, IBMT) or physical exercise (PE) experience to demonstrate their effects on brain, physiology and behavior. However, more research is necessary to conclusively rule out medical care as a mediator between education and health. Complete, transparent reporting of clinical trial data facilitates valid estimates of treatment efficacy. In the case of COVID-19 tests may induce more perceived anxiety than safety. Rochlin, D. H., Lee, C. M., Scheuter, C. n., Platchek, T. n., Kaplan, R. M., Milstein, A. n. Questioning the Benefit of Statins for Low-risk Populations-Medical Misinformation or Scientific Evidence? Cape Town, South Africa . C-terminal Agrin Fragment (CAF) has been proposed as a potential circulating biomarker for predicting changes in physical function among older adults. Early diagnosis does not assure application of an intervention that alters the pathway toward demise. View details for DOI 10.1007/s12603-015-0474-3, View details for Web of Science ID 000364577300008, View details for PubMedCentralID PMC4682669. Yet U.S. citizens lag behind their global peers in life expectancy and quality of life. Consistent with prior research, the AS incidence rate was greater in the White population than the Black population (aOR = 1.39, 95% CI 1.01 - 1.66, p = 0.04).CONCLUSION: In this study population, the incidence of AS was similar for the sexes. Identifying modifiable determinants of fat mass and muscle strength in older adults is important given their impact on physical functioning and health. in terms of outcomes that are meaningful to patients. Covariates included clinic site, body mass index, age, sex, baseline score, comorbidity, and use of angiotensin receptor blockers or ACE inhibitors. We describe relationships that test scores have with those from interviewer-administered cognitive function tests and risk factors for cognitive deficits and describe performance measures (completeness, intraclass correlations [ICC]).Computer-based assessments of cognitive function had consistent relationships across the pilot and full-scale trial cohorts with interviewer-administered assessments of cognitive function, age, and a measure of physical function. In addition, enabling widespread access to common measures is necessary to accelerate future progress. For the next TRICARE contracts which will begin in 2023, the DoD asked its health-focused federal advisory committee, the Defense Health Board (DHB), to recommend how best to assess and prioritize leading value-based healthcare initiatives identified from private, public, and employer-based health plans. Robert M Kaplan Boca Raton, FL (Century Village West) AGE 70s AGE 70s Robert M Kaplan Boca Raton, FL (Century Village West) Aliases Bob L Kaplan Phone NumberAddressBackground Report Aliases Bob L Kaplan Addresses Preston a Boca Raton, FL Eagle Creek Ct Boca Raton, FL James St Aledo, TX Relatives Contributions of Health Care to Longevity: A Review of 4 Estimation Methods. Robert M Kaplan Catherine M Crespi Ely Dahan Josemanuel D Saucedo Casey Pagan Christopher S Saigal. View details for DOI 10.14283/jfa.2016.76, View details for Web of Science ID 000449826700002, View details for PubMedCentralID PMC4905714. View details for DOI 10.1007/s10552-020-01309-w. Linking among different measures and consensus on standard HRQoL measurement should now be prioritized. The relationship between race/ethnicity, other potential risk factors, and the risk of incident diabetes was estimated using Cox proportional hazards models from which hazard ratios (HRs) and 95% CIs were computed.Participants were aged 63 years on average at baseline. He also represents insurance carriers . In order to make better use of scarce resources, cost-effectiveness methodologies have been developed to evaluate how to produce the most health within the constraints of available resources. Find out more. View details for Web of Science ID 000337624300008, View details for PubMedCentralID PMC4057978, To evaluate the prevalence of respiratory impairment and dyspnea and their associations with objectively measured physical inactivity and performance-based mobility in sedentary older persons.Cross-sectional.Lifestyle Interventions and Independence for Elders Study.Community-dwelling older persons (n = 1,635, mean age 78.9) who reported being sedentary (<20 min/wk of regular physical activity and <125 min/wk of moderate physical activity in past month).Respiratory impairment was defined as low ventilatory capacity (forced expiratory volume in 1 second less than lower limit of normal (LLN)) and respiratory muscle weakness (maximal inspiratory pressure For those with lower baseline fatigue, no group differences in MMD (P=.36) or PMMD (P=.82) were found. Dismiss. Phone Numbers: 419-194-1606. Symptoms of lack of positive affect decreased more in men compared to women, particularly in those possessing the 5-HTT L allele, but the effect did not differ by intervention arm. View details for DOI 10.1111/jgs.12738 Implementing the intervention in non-research settings may reduce costs further. #204. Join now Sign in . Additionally, NDYN-O demonstrated higher diastolic blood pressure compared with DYN-O (70.910.1 vs 67.79.7, P.001). People Projects Discussions . The objective of this study is to describe and examine correlates of health-related quality of life in this population subgroup using baseline data from a larger intervention study.The Lifestyle Interventions and Independence for Elders-Pilot study (LIFE-P) was a randomized controlled trial that compared a physical activity intervention to a non-exercise educational intervention among 424 older adults at risk for disability. March Wunderkammer Auction 9th - 19th March. At baseline, the 2 groups were well balanced by age, comorbidity, and baseline eGFRCysC. View details for DOI 10.1093/milmed/usab271. Whites, blacks, and Hispanics with all factors (i.e., weight, physical activity, dietary quality, and smoking) in the low-risk category had 60, 69, and 63% lower risk for incident diabetes. No significant effect on event-free survival was associated with individual therapy alone. Wilson, D. K., Kaufmann, P., Kaplan, R. M., Davidson, K. NIH behavioral and social sciences research support: 1980-2016. A., Bailey, C., Charpentier, P., Hawthorne-Jones, G., Mignosa, B., Lewis, L., Williamson, J., Hendrie, H. C., Rapp, S. R., Verghese, J., Woolard, N., Espeland, M., Jennings, J., Wilson, V. K., Pepine, C. J., Ariet, M., Handberg, E., Deluca, D., Hill, J., Szady, A., Chupp, G. L., Flynn, G. M., Hankinson, J. L., Fragoso, C., Groessl, E. J., Kaplan, R. M., Lifestyles Intervention Independen. Prior to the onset of training, 31.4% of participants noted slight conflict with being able to meet the demands of the program and 6.4% indicated that the degree of conflict would be moderate. The role of economic analyses in promoting adoption of behavioral and psychosocial interventions in clinical settings. In the 14% of records that contained results, the new data provided in the ClinicalTrials.gov records did not change the results or conclusions of the reviews. However, it is unclear whether these two forms of training share the same underlying mechanisms. The subjective perception of objective risks is calculated from the same 22 tables by exchanging the X- and Y-axes. The mean number of counts per minute of daily PA was not significantly associated with HCHD risk in any model (P>0.05). The authors wish to acknowledge the support and work done on this project by Christopher Davies Junior. Physical activity is an effective means of intervening on self-efficacy and satisfaction with physical function in older adults with impaired lower extremity functioning.
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